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Upon ligand engagement, CSF1R undergoes homodimerization, conformational rearrangement, and autophosphorylation of tyrosine residues within its juxtamembrane domain (JMD)

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Potential Side Effects While Retatrutide has shown promising results, some participants in clinical trials have reported side effects, including: Gastrointestinal Issues: Nausea, vomiting, diarrhea, or constipation, particularly in the early weeks of treatment